Abstract
With the advent of the era of Big Data, the traditional teaching mode has been changed greatly, and it opens up a new teaching approach for classroom teaching. Under the perspective of the era of Big Data, and based on the analysis of the characteristics of the era of large data and the characteristics of the traditional teaching mode, the reform and innovate of chemistry teaching mode was taken from four aspects: teaching form innovation, curriculum system optimization, teaching staff construction and teaching evaluation mode reform, it can provide a theoretical reference for the teaching staff in order to improve the quality of classroom teaching.